Desodin is a preparation of desloratadine. It is a metabolite of loratadine. Desloratadine is a long acting tricyclic histamine antagonist with selective H1-receptor antagonist activity. Desloratadine inhibits histamine release from human mast cells in vitro.
 

Desodin is indicated for the following conditions 

• Allergic rhinitis: For the relief of the nasal and non-nasal

        symptoms of allergic rhinitis (seasonal and perennial).

• Chronic idiopathic urticaria: For the symptomatic relief of

          pruritus, reduction in the number of hives, and size of hives.
 

Adult and adolescent over 12 years: 5 mg once daily

Child 6-11 years : 2.5 mg daily

In patients with liver or renal impairment, a starting dose of 5 mg at every alternative day is recommended.

Desodin tablets may be taken with or without food.

Desloratadine is contraindicated in patients who are hypersensitive to any of its ingredients, or to loratadine.
 

Pregnant women: There is no adequate and well-controlled studies of the uses of desloratadine in pregnancy. So desloratadine should be used during pregnancy only if clearly indicated.
Lactating mother: It is excreted in human breast milk. Therefore, it is not recommended for lactating mothers.

Drowsiness, sedation, fatigue, headache, psychomotor impairment, urinary retention, dry mouth, blurred vision, gastro-intestinal disturbances, palpitations, arrhythmias, hypotension, hypersensitivity reactions (including bronchospasm, angioedema, and anaphylaxis, rashes and photosensitivity reactions), extrapyramidal effects, dizziness, confusion, depression, sleep disturbances, tremor, convulsions, blood disorders, and liver dysfunction.
 

Alcohol enhances the sedative effect of desloratadine. Erythromycin, ketoconazole, cimetidine & amprenavir may increase plasma concentration of loratadine.
 

Antihistamine should be used with caution in prostatic hypertrophy, urinary retention, glaucoma, and pyloroduodenal obstruction. It should be used with caution in hepatic disease and dose reduction may be necessary in renal impairment. Caution may be required in epilepsy and porphyria. Children and the elderly are more susceptible to side effects.
 

Store in a cool and dry place, away from light. Keep out of
reach of children.
 

Desodin tablet: Box containing 5 strips of 10 tablets each. Each film coated tablet contains desloratadine INN 5 mg.
Desodin syrup: Bottle containing 60ml syrup, Each 5 ml syrup contains desloratadine INN 2.5 mg.



Manufactured by:
ESKAYEF BANGLADESH LTD
DHAKA, BANGLADESH
® REGD.TRADEMARK