Mycofin cream is the preparation of terbinafine hydrochloride, which is a synthetic antifungal compound. Terbinafine is an allylamine which has a broad spectrum antifungal activity. At low concentrations terbinafine is fungicidal against dermatophytes, moulds and certain dimorphic fungi. The activity against yeasts is fungicidal or fungistatic depending on the species. Terbinafine interferes with fungal sterol biosynthesis and it acts by inhibition of squalene epoxidase in the fungal cell membrane.

• Fungal infections of skin caused by dermatophytes such as Trichophyton (e.g. T. rubrum, T. mentagrophytes, T. verrucosum, T. violaceum) and Epidermophyton floccosum.
• Yeast infections of the skin, principally those caused by Candida albicans.
• Pityriasis (tinea) versicolor due to pityrosporum orbiculare (also known as malassezia furfur).

Mycofin cream can be applied once or twice daily. Cleanse and dry the affected areas thoroughly before treating with Mycofin cream. Apply the cream to the affected skin and surrounding area in a thin layer and rub in lightly. In the case of intertriginous infections (submammary, interdigital, intergluteal, inguinal) the application may be covered with gauze, especially at night.

• Tinea corporis, cruris (ringworm of the body, jock itch): 1 to 2 weeks
• Tines pedis (athlete's foot): 2 to 4 weeks
• Cutaneous candidiasis (skin thrush): 1 to 2 weeks
• Pityriasis versicolor: 2 weeks

Mycofin cream is contraindicated in individuals who have known or suspected hypersensitivity to terbinafine or any of its components.

Mycofin cream is only for external use. Contact with eyes should be avoided.

Redness, itching or stinging may occur at the site of application. These symptoms must be distinguished from allergic reaction which are rare but require discontinuation.

Potential interactions between terbinafine, and other drugs have not been systematically evaluated.

PREGNANCY: No adequate data available regarding uses of terbinafine in pregnancy. It can be used in pregnancy only if potential benefit outweighs risks.

LACTATION: It is excreted in human milk. It is advised to avoid in lactating women.
 

Keep away from light, store in a cool and dry place. Keep out of reach of children.

Mycofin cream: Tube containing 5 g cream. Each gram cream contains terbinafine hydrochloride INN equivalent to 10 mg terbinafine.



Manufactured by:
ESKAYEF BANGLADESH LTD
GAZIPUR, BANGLADESH
® REGD.TRADEMARK